PESHAWAR: Pakistani intelligence officials say an American missile attack has killed five suspected Islamist militants close to the Afghan border.

The attack late on Sunday in North Waziristan was the fourth in less than a week, signaling that Washington has no intention of heeding demands by Islamabad to stop the strikes.

The officials said five missiles hit a vehicle and a house in Makeene Kili village close to the town of Miran Shah.

They spoke on condition of anonymity because they were not allowed to give their names to the media.

Relations between Pakistan and the United States are fractured over Islamabad's refusal to reopen US and NATO supply lines to neighbouring Afghanistan that have been blocked since November.